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CB[n] host-guest chemistry

Tabet, A.; Gebhart, T.; Wu, G.; Readman, C.; Smela, M. P.; Rana, V. K.; Baker, C.; Bulstrode, H.; Anikeeva, P.; Rowitch, D. H.; Scherman, O. A. "Applying Support-Vector Machine Learning Algorithms towards Predicting Host-Guest Interactions with Cucurbit[7]uril", Phys. Chem. Chem. Phys., 2020, 22, 14976–14982. (read here)

Wu, G.; Huang, Z.; Scherman, O. A.; "Quantitative Supramolecular Heterodimerization for Efficient Energy Transfer", Angew. Chem. Int. Ed., 2020, 59, 15963–15967. (read here)

McCune, J. A.; Kuehnel, M. F.; Reisner, E.; Scherman, O. A.; "Stimuli Mediated Ultrastable Radical Formation", Chem, 2020, 6, 1819–1830. (read here)

Huang, Z.; Chen, X.; Wu, G.; Metrangolo, P.; Whitaker, D.; McCune, J.A.; Scherman, O.A. “Host- Enhanced Phenyl-Perfluorophenyl Polar-π Interactions”, J. Am. Chem. Soc., 2020, 142, 7356–7361. (read here)

Barrow, S.J.; Palmer, A.; de Nijs, B.; Chikkaraddy, R.; Bowman, R.W.; Baumberg, J. J.; Scherman, O.A. "Nanometer Control in Plasmonic Systems Through Discrete Layer-By-Layer Macrocycle-Cation Deposition", Nanoscale, 2020, 12, 8706–8710. (read here)

McCune, J.A.; Mommer, S.; Parkins, C.C; Scherman, O.A. "Design Principles for Aqueous Interactive Materials: Lessons from Small Molecules and Stimuli-Responsive Systems", Adv. Mater., 2020, 32, 1906890. (read here)

Wu, G.; Bae, Y.J.; Olesińska, M.; Antón-Garćıa, D.; Szabó, I.; Rosta, E.; Wasielewski, M.R.; Scherman, O.A. "Controlling the Structure and Photophysics of Fluorophore Dimers Using Multiple Cucurbit[8]uril Clampings", Chem. Sci., 2020, 11, 812–825. (read here)

Barrio, J.; Liu, J.; Brady, R.A.; Tan, C.S.; Chiodini, S.; Ricci, M.; Fernández-Leiro, R.; Tsai, C.J.; Vasileiadi, P.; Michele, L.D.; Lairez, D.; Toprakcioglu, C.; Scherman, O.A. "Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to Nanofibers", J. Am. Chem. Soc., 2019, 141, 14021–14025. (read here)

Wu, G.; Szabó, I.; Rosta, E.; Scherman, O.A. "Cucurbit[8]uril-Mediated Pseudo [2, 3] Rotaxanes", Chem. Commun., 2019, 55, 13227–13230. (read here)

Barrow, S.J.; Assaf, K.I.; Palma, A.; Nau, W.M.; Scherman, O.A. "Preferential Binding of Unsaturated Hydrocarbons in Aryl-Bisimidazolium·Cucurbit[8]uril Complexes Furbishes Evidence for Small-Molecule Interactions", Chem. Sci., 2019, 10, 10240–10246. (read here)

Olesińska, M.; Wu, G.; Gómez-Cola, S.; Antón-Garćıa, D.; Szabó, I.; Rosta, E.; Scherman, O.A. "Modular Supramolecular Dimerization of Optically Tunable Extended Aryl Viologens", Chem. Sci., 2019, 10, 8806–8811. (read here)

Wu, G.; Clarke, D.E.; Wu, C.; Scherman, O.A. "Oligopeptide-CB[8] Complexation with Switchable Binding Pathways", Org. Biomol. Chem., 2019, 17, 3514–3520. (read here)

Appel, E.A.; Biedermann, F.; Hoogland, D.; del Barrio, J.; Driscoll, M.D.; Hay, S.; Wales, D.J.; Scherman, O.A. "Decoupled Associative and Dissociative Processes in Strong Yet Highly Dynamic Host-Guest Complexes", J. Am. Chem. Soc., 2017, 139, 12985–12993. (read here)

Palma, A.; Artelsmair, M.; Wu, G.; Barrow, S.J.; Lu, X.; Uddin, N.; Rosta, E.; Masson, E.; Scherman, O.A. "Cucurbit[7]uril as a Supramolecular Artificial Enzyme for Diels-Alder Reactions", Angew. Chem. Int. Ed., 2017, 56, 5688–15692. (read here)

Sonzini, S.; McCune, J.A.; Ravn, P.; Scherman, O.A.; van der Walle, C.F. "A Simple Supramolecular Assay for Drug Detection in Urine", Chem. Commun., 2017, 53, 8842–8845. (read here)

McCune, J.A.; Kunz, S.; Olesińska, M.; Scherman, O.A. "DESolution of CD and CB Macrocycles", Chem. Eur. J., 2017, 23, 8601–8604. (read here)

Wu, G.; Olesińska, M.; Wu, Y.; Matak-Vinkovic, D.; Scherman, O.A. "Mining 2:2 Complexes from 1:1 Stoichiometry: Formation of Cucurbit[8]uril-Diarylviologen Quaternary Complexes Favored by Electron-Donating Substituents", J. Am. Chem. Soc., 2017, 139, 3202–3208. (read here)

McCune, J.A.; Rosta, E.; Scherman, O.A. "Modulating the Oxidation of Cucurbit[n]urils", Org. Biomol. Chem., 2017, 15, 998–1005. (read here)

Sonzini, S.; Stanyon, H.F.; Scherman, O.A. "Decreasing Amyloid Toxicity Through an Increased Rate of Aggregation", Phys. Chem. Chem. Phys., 2017, 19, 1458–1465. (read here)

Ryan, S.T.J.; del Barrio, J.; Suardiaz, R.; Ryan, D.F.; Rosta, E.; Scherman, O.A. "A Dynamic and Responsive Host in Action: Light-Controlled Molecular Encapsulation", Angew. Chem. Int. Ed., 2016, 55, 16096–16100. (read here)

Huang, Z.H.; Qin, K.; Deng, G.; Wu, G.L.; Bai, Y.H.; Xu, J.F.; Wang, Z.Q.; Yu, Z.W.; Scherman, O.A.; Zhang, X. "Supramolecular Chemistry of Cucurbiturils: Tuning Cooperativity with Multiple Noncovalent Interactions from Positive to Negative", Langmuir, 2016, 32, 12352–12360. (read here)

Sonzini, S.; Marcozzi, A.; Gubeli, R.J.; van der Walle, C.F.; Ravn, P.; Herrmann, A.; Scherman, O.A. "High Affinity Recognition of a Selected Amino Acid Epitope within a Protein by Cucurbit[8]uril Complexation", Angew. Chem. Int. Ed., 2016, 55, 14000–14004. (read here)

Gubeli, R.J.; Sonzini, S.; Podmore, A.; Ravn, P.; Scherman, O.A.; van der Walle, C.F. "Selective, Non-Covalent Conjugation of Synthetic Peptides with Recombinant Proteins Mediated by Host-Guest Chemistry", Chem. Commun., 2016, 52, 4235–4238. (read here)

Del Barrio, J.; Ryan, S.T.J.; Jambrina, P.G.; Rosta, E.; Scherman, O.A. "Light-Regulated Molecular Trafficking in a Synthetic Water-Soluble Host", J. Am. Chem. Soc., 2016, 138, 5745–5748. (read here)

Sigle, D.O.; Kasera, S.; Herrmann, L.O.; Palma, A.; de Nijs, B.; Benz, F.; Mahajan, S.; Baumberg, J.J.; Scherman, O.A. "Observing Single Molecules Complexing with Cucurbit[7]uril Through Nanogap-SERS", J. Phys. Chem. Lett., 2016, 7, 704–710. (read here)

Ryan, S.T.J.; Young, R.M.; Henkelis, J.J.; Hafezi, N.; Vermeulen, N. A.; Hennig, A.; Dale, E.D.; Wu, Y.; Krzyaniak, M.D.; Fox, A.; Nau, W.M.; Wasielewki, M. R.; Stoddart, J.F.; Scherman, O.A. "Energy and Electron Transfer Dynamics Within a Series of Perylene Diimide/Cyclophane Systems", J. Am. Chem. Soc., 2015, 137, 15299–15307. (read here)

Barrow, S.J.; Kasera, S.; Rowland, M.J.; del Barrio, J.; Scherman, O.A. "Cucurbituril-Based Molecular Recognition", Chem. Rev., 2015, 115, 12320–12406. (read here)

Zheng, L.; Sonzini, S.; Ambarwati, M.; Rosta, E.; Scherman, O.A.; Herrmann, A. "Turning Cucurbit[8]uril into a Supramolecular Nanoreactor for Asymmetric Catalysis", Angew. Chem. Int. Ed., 2015, 54, 13007–13011. (read here)

Nuzzo, J.A.; Scherman, O.A.; Mazzei, P.; Piccolo, A. "pH-Controlled Release of Auxin Plant Hormones from Cucurbit[7]uril Macrocycle", Chem. Biol. Technol. Agric., 2014, 1, 1–8. (read here)

Kasera, S.; Herrmann, L.O.; del Barrio, J.; Baumberg, J.J.; Scherman, O.A. "Quantitative Multiplexing with Nano-Self-Assemblies in SERS", Sci. Rep., 2014, 4, 6785. (read here)

Hu, C.; Lan, Y.; Tian, F.; West, K.R.; Scherman, O.A. "Facile Method for Preparing Surface-Mounted Cucurbit[8]uril-Based Rotaxanes", Langmuir, 2014, 30, 10926–10932. (read here)

Ryan, S.T.; del Barrio, J.; Ghosh, I.; Biedermann, F.; Lazar, A.I.; Lan, Y.; Coulston, R.J.; Nau, W.M.; Scherman, O.A. "Efficient Host-Guest Energy Transfer in Polycationic Cyclophane-Perylene Diimide Complexes in Water", J. Am. Chem. Soc., 2014, 136, 9053–9060. (read here)

Kasera, S.; Walsh, Z.; del Barrio, J.; Scherman, O.A. "A Selective Supramolecular Photochemical Sensor for Dopamine", Supramolecular Chemistry, 2014, 26, 280–285. (read here)

Biedermann, F.; Vendruscolo, M.; Scherman, O.A.; De Simone, A.; Nau, W.M. "Cucurbit[8]uril and Blue-Box: High-Energy Water Release Overwhelms Electrostatic Interactions", J. Am. Chem. Soc., 2013, 135, 14879–14888. (read here)

 

Sonzini, S.; Ryan, S.T.J.; Scherman, O.A. "Supramolecular Dimerisation of Middle-Chain Phe Pentapeptides via CB[8] Host-Guest Homoternary Complex Formation", Chem. Commun., 2013, 49, 8779–8781. (read here)

Lee, T-C.; Kalenius, E.; Lazar, A.I.; Assaf, K.I.; Kuhnert, N.; Grün, C.H.; Jänis, J.; Scherman, O.A.; Nau, W.M. "Chemistry Inside Molecular Containers in the Gas Phase", Nat. Chem., 2013, 5, 376–382. (read here)

Tian, F.; Jiao, D.; Biedermann, F.; Scherman, O.A. "Orthogonal Switching of a Single Supramolecular Complex", Nat. Commun., 2012, 3, 1207. (read here)

 

Kasera, S.; Biedermann, F.; Baumberg, J.J.; Scherman, O.A.; Mahajan, S. "Quantitative SERS Using the Sequestration of Small Molecules Inside Precise Plasmonic Nano-Constructs", Nano Lett., 2012, 12, 5924–5928. (read here)

 

Appel, E.A.; Rowland, M.J.; Loh, X.J.; Heywood, R.M.; Watts, C.; Scherman, O.A. "Enhanced Stability and Activity of Temozolomide in Primary Glioblastoma Multiforme Cells with Cucurbit[n]uril", Chem. Commun. 2012, 48, 9843–9845. (read here)

Biedermann, F.; Uzunova, V.D.; Scherman, O.A.; Nau, W.M.; De Simone, A. "Release of High-Energy Water as the Driving Force for the High-Affinity Binding of Cucurbit[n]urils", J. Am. Chem. Soc., 2012, 134, 15318–15323. (read here)

 

Jiao, D.; Scherman, O.A. "Isolation of Cucurbit[n]uril Homologues with Imidazolium Salts in a Recyclable Manner", Green Chem., 2012, 14, 2445–2449. (read here)

 

Biedermann, F.; Elmalem, E.; Ghosh, I.; Nau, W.N.; Scherman, O.A. "Strongly Fluorescent, Switchable Perylene-bisdiimide (PDI) Host-Guest Complexes with Cucurbit[8]uril in Water", Angew. Chem. Int. Ed., 2012, 51, 7739–7743. (read here)

 

Biedermann, F.; Scherman, O.A. "Cucurbit[8]uril Mediated Donor-Acceptor Ternary Complexes: A Model System for Studying Charge-Transfer Interactions", J. Phys. Chem. B, 2012, 116, 2842–2849. (read here)

Zhao, N.; Lloyd, G.O.; Scherman, O.A. "Monofunctionalised Cucurbit[6]uril Synthesis Using Imidazolium Host-Guest Complexation", Chem. Commun., 2012, 48, 3070–3072. (read here)

 

Cziferszky, M.; Biedermann, F.; Kalberer, M.; Scherman, O.A. "Probing the Stability of Multicomponent Self-Assembled Architectures Based on Cucurbit[8]uril in the Gas Phase", Org. Biomol. Chem., 2012, 10, 2447–2452. (read here)

 

Jiao, D.; Biedermann, F.; Scherman, O.A. "Size Selective Supramolecular Cages from Aryl-Bisimidazolium Derivatives and Cucurbit[8]uril", Org. Lett., 2011, 13, 3044–3047. (read here)

 

Tian, F.; Cziferszky, M.; Jiao, D.; Wahlstrom, K.; Geng, J.; Scherman, O.A. "Peptide Separation Through a CB[8]-Mediated Supramolecular Trap-and-Release Process", Langmuir, 2011, 27, 1387–1390. (read here)

 

Biedermann, F.; Rauwald, U.; Cziferszky, M.; Williams, K.A.; Gann, L.; Guo, B.Y.; Urbach, A.R.; Bielawski, C.W.; Scherman, O.A. "Benzobis(imidazolium) Salts: Chemically Stable, Intrinsically Fluorescent Alternatives to Viologens for Applications in Supramolecular Chemistry", Chem. Eur. J., 2010, 16, 13716–13722. (read here)

Mahajan, S.; Lee, T.C.; Biedermann, F.; Hugall, J.T.; Baumberg, J.J.; Scherman, O.A. "Raman and SERS Spectroscopy of Cucurbit[n]urils", Phys. Chem. Chem. Phys., 2010, 12, 10429–10433. (read here)

Rauwald, U.; Biedermann, F.; Deroo, S.; Robinson, C.V.; Scherman, O.A. "Correlating Solution Binding and ESI-MS Stabilities by Incorporating Solvation Effects in a Confined Cucurbit[8]uril System", J. Phys. Chem. B, 2010, 114, 8606–8615. (read here)

Lee, T.C.; Scherman, O.A. "Formation of Dynamic Aggregates in Water by Cucurbit[5]uril Capped with Gold Nanoparticles", Chem. Commun., 2010, 46, 2338–2440. (read here)

Jiao, D.; Zhao, N.; Scherman, O.A. "A 'Green' Method for Isolation of Cucurbit[7]uril via a Solid State Metathesis Reaction", Chem. Commun., 2010, 46, 2007–2009. (read here)

Zhao, N.; Liu, L.; Biedermann, F.; Scherman, O.A. "Binding Studies on CB[6] with a Series of 1-Alkyl-3-methylimidazolium Ionic Liquids in an Aqueous System", Chem. Asian J., 2010, 5, 530–537. (read here)

Liu, L.; Nouvel, N.; Scherman, O.A. "Controlled Catch and Release of Small Molecules with Cucurbit[6]uril via a Kinetic Trap", Chem. Commun., 2009, 22, 3243–3245. (read here)

Deroo, S.; Rauwald, U.; Robinson, C.V.; Scherman, O.A. "Discrete, Multi-Component Complexes with Cucurbit[8]uril in the Gas-Phase", Chem. Commun., 2009, 6, 644–646. (read here)

Liu, L.; Zhao, N.; Scherman, O.A. "Ionic Liquids as Novel Guests for Cucurbit[6]uril in Neutral Water", Chem. Commun., 2008, 9, 1070–1072. (read here)

Scherman Lab

Melville Laboratory for Polymer Synthesis

University of Cambridge

Website design and content by Dr Jade A. McCune

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