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Drug delivery and release

Parkins, C. C.; McAbee, J. H.; Ruff, L.; Wendler, A.; Mair, R.; Gilbertson, R. J.; Watts, C.; Scherman, O. A. "Mechanically Matching the Rheological Properties of Brain Tissue for Drug-Delivery in Human Glioblastoma Models", Biomaterials, 2021, 276, 120919. (read here)

Tabet, A.; Mommer, S.; Vigil, J.; Hallou, C.; Bulstrode, H.; Scherman, O.A. "Mechanical Characterization of Human Brain Tissue and Soft Dynamic Gels Exhibiting Electromechanical Neuro-Mimicry", Adv. Healthc. Mater., 2019, 8, 1900068. (read here)

Tabet, A.; Jensen, M.P.; Parkins, C.C.; Patil, P.G.; Watts, C.; Scherman, O.A. "Designing Next-Generation Local Drug Delivery Vehicles for Glioblastoma Adjuvant Chemotherapy: Lessons from the Clinic", Adv. Healthc. Mater., 2019, 8, 1801391. (read here)

Rowland, M.J.; Parkins, C.C.; McAbee, J.H.; Kolb, A.K.; Hein, R.; Loh, X.J.; Watts, C.; Scherman, O.A. "An Adherent Tissue-inspired Hydrogel Delivery Vehicle Utilised in Primary Human Glioma Models", Biomaterials, 2018, 179, 199–208. (read here)

Rowland, M.J.; Atgie, M.; Hoogland, D.; Scherman, O.A. "Preparation and Supramolecular Recognition of Multivalent Peptide–Polysaccharide Conjugates by Cucurbit[8]uril in Hydrogel Formation", Biomacromolecules, 2015, 16, 2436–2443. (read here)

Appel, E.A.; Forster, R.A.; Rowland, M.J.; Scherman, O.A. "The Control of Cargo Release from Physically Crosslinked Hydrogels by Crosslink Dynamics", Biomaterials, 2014, 35, 9897–9903. (read here)

Appel, E.A.; Forster, R.A.; Koutsioubas, A.; Toprakcioglu, C.; Scherman, O.A. "Activation Energies Control the Macroscopic Properties of Physically Cross-Linked Materials", Angew. Chem. Int. Ed., 2014, 53, 10038–10043. (read here)

Rowland, M.J.; Appel, E.A.; Coulston, R.J.; Scherman, O.A. "Dynamically Crosslinked Materials via Recognition of Amino Acids by Cucurbit[8]uril", J. Mater. Chem. B, 2013, 1, 2904–2910. (read here)

Appel, E.A.; Rowland, M.J.; Loh, X.J.; Heywood, R.M.; Watts, C.; Scherman, O.A. "Enhanced Stability and Activity of Temozolomide in Primary Glioblastoma Multiforme Cells with Cucurbit[n]uril", Chem. Commun., 2012, 48, 9843–9845. (read here)


Appel, E.A.; del Barrio, J.; Loh, X.J.; Scherman, O.A. "Supramolecular Polymeric Hydrogels", Chem. Soc. Rev., 2012, 41, 6195–6214. (read here)

Appel, E.A.; Loh, X.J.; Jones, S.T.; Biedermann, F.; Dreiss, C.A.; Scherman, O.A. "Ultrahigh-Water-Content Supramolecular Hydrogels Exhibiting Multistimuli Responsiveness", J. Am. Chem. Soc., 2012, 134, 11767–11773. (read here)


Appel, E.A.; Loh, X.J.; Jones, S.T.; Dreiss, C.A.; Scherman, O.A. "Sustained Release of Proteins from High-Water-Content Supramolecular Polymer Hydrogels", Biomaterials, 2012, 33, 4646–4652. (read here)


Appel, E.A.; Scherman, O.A. "Dynamic Supramolecular Polymers", Chapter 6.16 in Comprehensive Polymer Science, Volume 6: Macromolecular Architectures and Soft Nano-Objects; Mueller, A.; Wooley, K., Vol. 6 Eds.; Elsevier-Ltd, 2012, 587–628. (read here)

Appel, E.A.; Rauwald, U.; Jones, S.; Zayed, J.M.; Scherman, O.A. "Supramolecular Crosslinked Networks via Host-guest Complexation with Cucurbit[8]uril", J. Am. Chem. Soc., 2010, 132, 14251–14260. (read here)

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