top of page

CB[n] Polymer Networks

O'Neill, S.J.K.; Huang, Z.; Ahmed, M.H.; Boys, A.J.; Velasco-Bosom, S.; Li, J.; Owens, R.M.; McCune, J.A.; Malliaras, G.; Scherman, O.A. Tissue-Mimetic Supramolecular Polymer Networks for Bioelectronics. Adv. Mat., 2023, 35, 2207634. (read here)

 

Whitaker, D.J.; Park, J.; Ueda, C.; Wu, G.; Harada, A.; Matsuba, G.; Takashima, Y.; Scherman, O.A. "Water Content and Guest Size Dictate the Mechanical Properties of Cyclodextrin Mediated Hydrogels," Polym. Chem., 2022, 13, 5127-5134. (read here)

 

Mommer, S.; Sokołowski, K.; Olesińska M.; Huang, Z.; Scherman, O.A. "Supramolecular Encapsulation of Redox-Active Monomers to Enable Free-Radical Polymerisation," Chem. Sci., 2022, 13, 8791-8796. (read here)

 

Cruz, M.V.; Shah, D.U.; Warner, N.C.; McCune, J.A.; Scherman, O.A. "Facile, Energy Efficient Microscale Fibrillation of Polyacrylamides under Ambient Conditions," Adv. Mater., 2022, 34, 2201577. (read here)

 

Huang, Z.; Chen, X.; O'Neill, S.; Wu, G.; Whitaker, D.J.; Li, J.; McCune, J.A.; Scherman, O.A. "Highly Compressible Glass-like Supramolecular Polymer Networks," Nat. Mater., 2022, 21, 103-109. (read here)

Parkins, C. C.; McAbee, J. H.; Ruff, L.; Wendler, A.; Mair, R.; Gilbertson, R. J.; Watts, C.; Scherman, O. A. "Mechanically Matching the Rheological Properties of Brain Tissue for Drug-Delivery in Human Glioblastoma Models", Biomaterials, 2021, 276, 120919. (read here)

Whitaker, D. J.; Huang, Z.; Longbottom, B.; Sala, R. L.; Wu, G.; Scherman, O. A. "Supramolecular Hydrogels Prepared From Fluorescent Alkyl Pyridinium Acrylamide Monomers and CB[8]", Polym. Chem., 2021, 12, 519–525. (read here)

Huang, Z.; Chen, X.; Wu, G.; Metrangolo, P.; Whitaker, D.; McCune, J.A.; Scherman, O.A. “Host- Enhanced Phenyl-Perfluorophenyl Polar-π Interactions”, J. Am. Chem. Soc., 2020, 142, 7356–7361. (read here)

Das, B.K.; Pramanik, B.; Chowdhuri, S.; Scherman, O.A.; Das, D. "Light-Triggered Syneresis of a Water Insoluable Peptide-Hydrogel Effectively Removes Small Molecule Waste Contaminants", Chem. Commun., 2020, 56, 3393–3396. (read here)

McCune, J.A.; Mommer, S.; Parkins, C.C; Scherman, O.A. "Design Principles for Aqueous Interactive Materials: Lessons from Small Molecules and Stimuli-Responsive Systems", Adv. Mater., 2020, 32, 1906890. (read here)

Meng, Z.; Liu, J.; Yu, Z.; Zhou, H.; Deng, X.; Abell, C.; Scherman, O.A. "Viscoelastic Hydrogel Microfibers Exploiting Cucurbit[8]uril Host–Guest Chemistry and Microfluidics", ACS Appl. Mater. Interfaces, 2020, 12, 17929–17935. (read here)

Rana, V.K.; Tabet, A.; Vigil, J.A.; Balzer, C.J.; Narkevicius, A.; Finlay, J.; Hallou, C.; Rowitch, D.H.; Bulstrode, H.; Scherman, O.A. "Cucurbit[8]uril-Derived Graphene Hydrogels", ACS Macro Lett., 2019, 8, 1629–1634. (read here)

Barrio, J.; Liu, J.; Brady, R.A.; Tan, C.S.; Chiodini, S.; Ricci, M.; Fernández-Leiro, R.; Tsai, C.J.; Vasileiadi, P.; Michele, L.D.; Lairez, D.; Toprakcioglu, C.; Scherman, O.A. "Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to Nanofibers", J. Am. Chem. Soc., 2019, 141, 14021–14025. (read here)

Tabet, A.; Mommer, S.; Vigil, J.; Hallou, C.; Bulstrode, H.; Scherman, O.A. "Mechanical Characterization of Human Brain Tissue and Soft Dynamic Gels Exhibiting Electromechanical Neuro-Mimicry", Adv. Healthc. Mater., 2019, 8, 1900068. (read here)

Tabet, A.; Jensen, M.P.; Parkins, C.C.; Patil, P.G.; Watts, C.; Scherman, O.A. "Designing Next-Generation Local Drug Delivery Vehicles for Glioblastoma Adjuvant Chemotherapy: Lessons from the Clinic", Adv. Healthc. Mater., 2019, 8, 1801391. (read here)

Tabet, A.; Forster, R.A.; Parkins, C.C.; Wu, G.; Scherman, O.A. "Modulating Stiffness with Photo-Switchable Supramolecular Hydrogels", Polym. Chem., 2019, 10, 467–472. (read here)

Qiao, H.; Jia, J.; Chen, W.; Di, B.; Scherman, O.A.; Hu, C. "Magnetic Regulation of Thermo-Chemotherapy from a Cucurbit[7]uril-Crosslinked Hybrid Hydrogel", Adv. Healthc. Mater., 2019, 8, 1801458. (read here)

Wang, Y.; Wang, S.; Zhang, S.; Scherman, O.A.; Baumberg, J.J.; Ding, T.; Xu, H. "Plasmon-Directed Polymerization: Regulating Polymer Growth With Light", Nano Research, 2018, 11, 6384. (read here)

Clarke, D.E.; Parmenter, C.D.J.; Scherman, O.A. "Tunable Pentapeptide Self-Assembled β-Sheet Hy- drogels", Angew. Chem. Int. Ed., 2018, 57, 7709–7713. (read here)

Liu, J.; Scherman, O.A. "Cucurbit[n]uril Supramolecular Hydrogel Networks as Tough and Healable Adhesives", Adv. Funct. Mater., 2018, 28, 1800848. (read here)

Rowland, M.J.; Parkins, C.C.; McAbee, J.H.; Kolb, A.K.; Hein, R.; Loh, X.J.; Watts, C.; Scherman, O.A. "An Adherent Tissue-inspired Hydrogel Delivery Vehicle Utilised in Primary Human Glioma Models", Biomaterials2018, 179, 199–208. (read here)

Appel, E.A.; Biedermann, F.; Hoogland, D.; del Barrio, J.; Driscoll, M.D.; Hay, S.; Wales, D.J.; Scherman, O.A. "Decoupled Associative and Dissociative Processes in Strong Yet Highly Dynamic Host-Guest Complexes", J. Am. Chem. Soc., 2017, 139, 12985–12993. (read here)

Liu, J.; Tan, C.S.Y.; Lan, Y.; Scherman, O.A. "Toward a Versatile Toolbox for Cucurbit[n]uril-Based Supramolecular Hydrogel Networks Through in situ Polymerization", J. Polym. Sci. Part A, Polym. Chem., 2017, 55, 3105–3109. (read here)

Liu, J.; Tan, C.S.Y.; Yu, Z.Y.; Li, N.; Abell, C.; Scherman, O.A. "Tough Supramolecular Polymer Networks with Extreme Stretchability and Fast Room-Temperature Self-Healing", Adv. Mater., 2017, 29, 1605325. (read here)

Ding, T.; Mertens, J.; Lombardi, A.; Scherman, O.A.; Baumberg, J.J. "Light-Directed Tuning of Plasmon Resonances via Plasmon-Induced Polymerization Using Hot Electrons", ACS Photonics, 2017, 4, 1453–1458. (read here)

Liu, J.; Tan, C.S.Y.; Yu, Z.Y.; Lan, Y.; Abell, C.; Scherman, O.A. "Biomimetic Supramolecular Polymer Networks Exhibiting Both Toughness and Self-Recovery", Adv. Mater., 2017, 29, 1604951. (read here)

Tan, C.S.Y.; Agmon, G.; Liu, J.; Hoogland, D.; Janeček, E.R.; Appel, E.; Scherman, O.A. "Distinguishing Relaxation Dynamics in Transiently Crosslinked Polymeric Networks", Polym. Chem., 2017, 8, 5336–5343. (read here)

Liu, J.; Tan, C.S.Y.; Lan, Y.; Scherman, O.A. "Aqueous Polymer Self-Assembly Based on Cucurbit[n]uril-Mediated Host-Guest Interactions", Macromol. Chem. Phys.2016, 217, 319–332. (read here)

Liu, C.; Xiang, G.; Wu, Y.; Barrow, S.J.; Rowland, M.J.; Clarke, D.E.; Wu, G.; Scherman, O.A. "Hybrid Organic-Inorganic Supramolecular Hydrogel Reinforced with CePO4 Nanowires", Polym. Chem., 2016, 7, 6485–6489. (read here)

Del Barrio, J.; Ryan, S.T.J.; Jambrina, P.G.; Rosta, E.; Scherman, O.A. "Light-Regulated Molecular Trafficking in a Synthetic Water-Soluble Host", J. Am. Chem. Soc., 2016, 138, 5745–5748. (read here)

Rowland, M.J.; Atgie, M.; Hoogland, D.; Scherman, O.A. "Preparation and Supramolecular Recognition of Multivalent Peptide–Polysaccharide Conjugates by Cucurbit[8]uril in Hydrogel Formation", Biomacromolecules, 2015, 16, 2436–2443. (read here)

Li, C.; Rowland, M.J.; Shao, Y.; Cao, T.; Chen, C.; Jia, H.; Zhou, X.; Yang, Z.; Scherman, O.A.; Liu, D. "Responsive Double Network Hydrogels of Interpenetrating DNA and CB[8] Host-Guest Supramolecular Systems", Adv. Mater., 2015, 27, 3298–3304. (read here)

Janeček, E.R.; McKee, J.R.; Tan, C.S.Y.; Nykanen, A.; Kettunen, M.; Laine, J.; Ikkala, O.; Scherman, O.A. "Hybrid Supramolecular and Colloidal Hydrogels Bridging Multiple Length Scales", Angew. Chem. Int. Ed., 2015, 54, 5383–5388. (read here)

Williams, P.E.; Jones, S.T.; Walsh, Z.; Appel, E.A.; Abo-Hamed, E.K.; Scherman, O.A. "Synthesis of Conducting Polymer-Metal Nanoparticle Hybrids Exploiting RAFT Polymerization", ACS Macro Lett., 2015, 4, 255–259. (read here)

Tan, C.S.Y.; del Barrio, J.; Liu, J.; Scherman, O.A. "Supramolecular Polymer Networks Based on Cucurbit[8]uril Host-Guest Interactions as Aqueous Photo-rheological Fluids", Polym. Chem., 2015, 6, 7652–7657. (read here)

Hu, C.; Tian, F.; Zheng, Y.; Tan, C.S.Y.; West, K.R.; Scherman, O.A. "Cucurbit[8]uril Directed Stimuli-Responsive Supramolecular Polymer Brushes for Dynamic Surface Engineering", Chem. Sci., 2015, 6, 5303–5310. (read here)

Wu, Y.; Lan, Y.; Liu, J.; Scherman, O.A. "Catalytic Polymeric Nanocomposites via Cucurbit[n]uril Host-Guest Interactions", Nanoscale, 2015, 7, 13416–13419. (read here)

Appel, E.A.; Forster, R.A.; Rowland, M.J.; Scherman, O.A. "The Control of Cargo Release from Physically Crosslinked Hydrogels by Crosslink Dynamics", Biomaterials, 2014, 35, 9897–9903. (read here)

Appel, E.A.; Forster, R.A.; Koutsioubas, A.; Toprakcioglu, C.; Scherman, O.A. "Activation Energies Control the Macroscopic Properties of Physically Cross-Linked Materials", Angew. Chem. Int. Ed., 2014, 53, 10038–10043. (read here)

Huang, Z.; Yang, L.; Liu, Y.; Wang, Z.; Scherman, O.A.; Zhang, X. "Supramolecular Polymerization Promoted and Controlled Through Self-Sorting", Angew. Chem. Int. Ed., 2014, 53, 5351–5355. (read here)

Biedermann, F.; Ross, I.; Scherman, O.A. "Host-Guest Accelerated Photodimerisation of Anthracene-Labeled Macromolecules in Water", Polym. Chem., 2014, 5, 5375–5382. (read here)

del Barrio, J.; Blasco, E.; Toprakcioglu, C.; Koutsiubas, A.; Scherman, O.A.; Oriol, L.; Sanchez-Somolinos, C. "Self-Assembly and Photoinduced Optical Anisotropy in Dendronized Supramolecular Azopolymers", Macromolecules, 2014, 47, 897–906. (read here)

Janecek, E.R.; Rauwald, U.; del Barrio, J.; Cziferszky, M.; Scherman, O.A. "A Facile Route to Viologen Functional Macromolecules Through Azide-Alkyne [3+2] Cycloaddition", Macromol. Rapid Commun., 2013, 34, 1547–1553. (read here)
 
del Barrio, J.; Horton, P.N.; Lairez, D.; Lloyd, G.O.; Toprakcioglu, C.; Scherman, O.A. "Photocontrol Over Cucurbit[8]uril Complexes: Stoichiometry and Supramolecular Polymers", J. Am. Chem. Soc., 2013, 135, 11760–11763. (read here)

Loh, X.J.; Scherman, O.A. (Editors) "Polymeric and Self Assembled Hydrogels: From Fundamental Understanding to Applications", Royal Society of Chemistry, 2013, ISBN: 9781849735629. (read here)

Rowland, M.J.; Appel, E.A.; Coulston, R.J.; Scherman, O.A. "Dynamically Crosslinked Materials via Recognition of Amino Acids by Cucurbit[8]uril", J. Mater. Chem. B, 2013, 1, 2904–2910. (read here)

Huang, F.; Scherman, O.A. "Supramolecular Polymers", Chem. Soc. Rev., 2012, 41, 5879–5880. (read here)

Appel, E.A.; del Barrio, J.; Loh, X.J.; Scherman, O.A. "Supramolecular Polymeric Hydrogels", Chem. Soc. Rev., 2012, 41, 6195–6214. (read here)

Appel, E.A.; Loh, X.J.; Jones, S.T.; Biedermann, F.; Dreiss, C.A.; Scherman, O.A. "Ultrahigh-Water-Content Supramolecular Hydrogels Exhibiting Multistimuli Responsiveness", J. Am. Chem. Soc., 2012, 134, 11767–11773. (read here)
 
Appel, E.A.; Loh, X.J.; Jones, S.T.; Dreiss, C.A.; Scherman, O.A. "Sustained Release of Proteins from High-Water-Content Supramolecular Polymer Hydrogels", Biomaterials, 2012, 33, 4646–4652. (read here)
 
Appel, E.A.; Scherman, O.A. "Dynamic Supramolecular Polymers", Chapter 6.16 in Comprehensive Polymer Science, Volume 6: Macromolecular Architectures and Soft Nano-Objects; Mueller, A.; Wooley, K., Vol. 6 Eds.; Elsevier-Ltd, 2012, 587–628. (read here)
 
Appel, E.A.; del Barrio, J.; Loh, X.J.; Dyson, J.; Scherman, O.A. "High Molecular Weight Polyacrylamides by ATRP: Enabling Advancements in Water-Based Applications", J. Polym. Sci. Part A, Polym. Chem., 2012, 50, 181–186. (read here)

Rauwald, U.; del Barrio, J.; Loh, X.J.; Scherman, O.A. "On-Demand" Control of Thermoresponsive Properties of Poly(N-isopropylacrylamide) with Cucurbit[8]uril Host-Guest Complexes", Chem. Commun., 2011, 47, 6000–6002. (read here)
 
Biedermann, F.; Appel, E.A.; del Barrio, J.; Gruendling, T.; Barner-Kowollik, C.; Scherman, O.A. "Post-polymerization Modification of Hydroxyl-Functionalized Polymers with Isocyanates", Macromolecules, 2011, 44, 4828–4835. (read here)

Geng, J.; Biedermann, F.; Zayed, J.M.; Tian, F.; Scherman, O.A. "Supramolecular Glycopolymers in Water: A Reversible Route Towards Multivalent Carbohydrate-Lectin Conjugates Using Cucurbit[8]uril", Macromolecules, 2011, 44, 4276–4281. (read here)

Biedermann, F.; Rauwald, U.; Zayed, J.M.; Scherman, O.A. "A Supramolecular Route for Reversible Protein-Polymer Conjugation", Chem. Sci., 2011, 2, 279–286. (read here)

Celiz, A.D.; Scherman, O.A. "A Facile Route to Ureidopyrimidinone-Functionalized Polymers via RAFT", J. Polym. Sci. A, Polym. Chem., 2010, 48, 5833–5841. (read here)

Appel, E.A.; Rauwald, U.; Jones, S.; Zayed, J.M.; Scherman, O.A. "Supramolecular Crosslinked Networks via Host-guest Complexation with Cucurbit[8]uril", J. Am. Chem. Soc., 2010, 132, 14251–14260. (read here)

Zayed, J.M.; Biedermann, F.; Rauwald, U.; Scherman, O.A. "Probing Cucurbit[8]uril-mediated Supramolecular Polymer Assembly in Water Using Diffusion NMR", Polym. Chem., 2010, 1, 1434–1436. (read here)

Geng, J.; Jiao, D.; Rauwald, U.; Scherman, O.A. "An Aqueous Supramolecular Side-Chain Polymer Designed for Molecular Loading", Australian J. Chem., 2010, 63, 627–630. (read here)

Celiz, A.D.; Scherman, O.A. "Controlled Ring-Opening Polymerization Initiated via Self-Complementary Hydrogen-Bonding Units", Macromolecules, 2008, 41, 4115–4119. (read here)

Rauwald, U.; Scherman, O.A. "Supramolecular Block Copolymers with Cucurbit[8]uril in Water", Angew. Chem. Int. Ed., 2008, 47, 3950–3953. (read here)

Scherman Lab

Melville Laboratory for Polymer Synthesis

University of Cambridge

Website design and content by Dr Jade A. McCune

bottom of page